Physical Properties | | | |
Molecular Weight: 397.603 g/mol | logS: -5.22988 | SlogP: 5.61257 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0212058 | Sterimol/B1: 2.62198 | Sterimol/B2: 3.46753 | Sterimol/B3: 4.19823 |
Sterimol/B4: 5.99162 | Sterimol/L: 23.6314 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 725.064 | Positive charged surface: 571.856 | Negative charged surface: 153.208 | Volume: 422.5 |
Hydrophobic surface: 666.802 | Hydrophilic surface: 58.262 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |