Physical Properties | | | |
Molecular Weight: 405.227 g/mol | logS: -7.61702 | SlogP: 5.784 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.154932 | Sterimol/B1: 2.71392 | Sterimol/B2: 5.43833 | Sterimol/B3: 5.86707 |
Sterimol/B4: 6.12821 | Sterimol/L: 13.3423 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 540.938 | Positive charged surface: 163.342 | Negative charged surface: 377.596 | Volume: 303.75 |
Hydrophobic surface: 322.826 | Hydrophilic surface: 218.112 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |