Physical Properties | | | |
Molecular Weight: 405.227 g/mol | logS: -7.61702 | SlogP: 5.784 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.15495 | Sterimol/B1: 2.7145 | Sterimol/B2: 5.43751 | Sterimol/B3: 5.868 |
Sterimol/B4: 6.12764 | Sterimol/L: 13.3461 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 539.585 | Positive charged surface: 163.45 | Negative charged surface: 376.134 | Volume: 303.625 |
Hydrophobic surface: 322.55 | Hydrophilic surface: 217.035 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |