Physical Properties | | | |
Molecular Weight: 421.803 g/mol | logS: -2.69621 | SlogP: 1.8665 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.185293 | Sterimol/B1: 3.43552 | Sterimol/B2: 5.20296 | Sterimol/B3: 5.47704 |
Sterimol/B4: 6.65576 | Sterimol/L: 13.8749 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 586.545 | Positive charged surface: 359.309 | Negative charged surface: 227.237 | Volume: 339.625 |
Hydrophobic surface: 411.065 | Hydrophilic surface: 175.48 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |