Physical Properties | | | |
Molecular Weight: 435.85 g/mol | logS: -5.38155 | SlogP: 4.2412 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0455557 | Sterimol/B1: 2.20249 | Sterimol/B2: 4.18801 | Sterimol/B3: 4.20224 |
Sterimol/B4: 6.2959 | Sterimol/L: 20.2926 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 636.164 | Positive charged surface: 276.04 | Negative charged surface: 360.124 | Volume: 347.875 |
Hydrophobic surface: 424.043 | Hydrophilic surface: 212.121 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |