Physical Properties | | | |
Molecular Weight: 421.823 g/mol | logS: -5.43751 | SlogP: 3.8337 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0560115 | Sterimol/B1: 2.12884 | Sterimol/B2: 2.94159 | Sterimol/B3: 4.47824 |
Sterimol/B4: 7.10693 | Sterimol/L: 19.3737 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 616.099 | Positive charged surface: 237.07 | Negative charged surface: 379.03 | Volume: 330.875 |
Hydrophobic surface: 392.394 | Hydrophilic surface: 223.705 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |