Physical Properties | | | |
Molecular Weight: 365.389 g/mol | logS: -4.12841 | SlogP: 2.23647 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0301425 | Sterimol/B1: 2.21983 | Sterimol/B2: 2.83465 | Sterimol/B3: 4.84291 |
Sterimol/B4: 6.03445 | Sterimol/L: 21.0671 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 647.441 | Positive charged surface: 424.953 | Negative charged surface: 217.391 | Volume: 337.625 |
Hydrophobic surface: 481.478 | Hydrophilic surface: 165.963 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |