Physical Properties | | | |
Molecular Weight: 417.534 g/mol | logS: -3.38361 | SlogP: 1.9864 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0346905 | Sterimol/B1: 2.41272 | Sterimol/B2: 3.11774 | Sterimol/B3: 4.5591 |
Sterimol/B4: 5.88863 | Sterimol/L: 22.7188 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 700.272 | Positive charged surface: 487.889 | Negative charged surface: 212.383 | Volume: 387.625 |
Hydrophobic surface: 549.54 | Hydrophilic surface: 150.732 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |