Physical Properties | | | |
Molecular Weight: 386.428 g/mol | logS: -4.09406 | SlogP: 2.10924 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.22128 | Sterimol/B1: 1.969 | Sterimol/B2: 2.76235 | Sterimol/B3: 6.84444 |
Sterimol/B4: 8.81637 | Sterimol/L: 13.2879 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 589.979 | Positive charged surface: 389.673 | Negative charged surface: 200.306 | Volume: 332.375 |
Hydrophobic surface: 443.517 | Hydrophilic surface: 146.462 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |