Physical Properties | | | |
Molecular Weight: 384.484 g/mol | logS: -6.78292 | SlogP: 4.43972 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0243284 | Sterimol/B1: 3.26222 | Sterimol/B2: 3.58703 | Sterimol/B3: 4.62282 |
Sterimol/B4: 5.97342 | Sterimol/L: 19.5253 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 655.325 | Positive charged surface: 378.435 | Negative charged surface: 276.89 | Volume: 342.5 |
Hydrophobic surface: 509.376 | Hydrophilic surface: 145.949 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |