Physical Properties | | | |
Molecular Weight: 384.496 g/mol | logS: -3.60899 | SlogP: 2.723 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.149827 | Sterimol/B1: 2.5299 | Sterimol/B2: 5.4217 | Sterimol/B3: 5.95729 |
Sterimol/B4: 6.49609 | Sterimol/L: 15.2443 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 570.364 | Positive charged surface: 327.453 | Negative charged surface: 242.911 | Volume: 335.875 |
Hydrophobic surface: 487.962 | Hydrophilic surface: 82.402 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |