Physical Properties | | | |
Molecular Weight: 401.575 g/mol | logS: -3.89465 | SlogP: 3.8762 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0818555 | Sterimol/B1: 2.35264 | Sterimol/B2: 2.56107 | Sterimol/B3: 6.23253 |
Sterimol/B4: 8.06878 | Sterimol/L: 20.0307 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 674.291 | Positive charged surface: 459.385 | Negative charged surface: 214.906 | Volume: 398.625 |
Hydrophobic surface: 572.315 | Hydrophilic surface: 101.976 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |