Physical Properties | | | |
Molecular Weight: 414.909 g/mol | logS: -5.86335 | SlogP: 3.0271 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0592431 | Sterimol/B1: 2.21215 | Sterimol/B2: 3.52241 | Sterimol/B3: 5.32679 |
Sterimol/B4: 7.02735 | Sterimol/L: 22.0371 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 715.711 | Positive charged surface: 439.01 | Negative charged surface: 276.701 | Volume: 395.25 |
Hydrophobic surface: 621.001 | Hydrophilic surface: 94.71 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |