Physical Properties | | | |
Molecular Weight: 395.313 g/mol | logS: -7.42739 | SlogP: 6.0995 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.227157 | Sterimol/B1: 2.56305 | Sterimol/B2: 5.51808 | Sterimol/B3: 6.14985 |
Sterimol/B4: 6.31598 | Sterimol/L: 14.2403 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 611.782 | Positive charged surface: 305.909 | Negative charged surface: 305.873 | Volume: 365.875 |
Hydrophobic surface: 552.594 | Hydrophilic surface: 59.188 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 0 | Acid groups: 0 | Basic groups: 3 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |