Physical Properties | | | |
Molecular Weight: 520.585 g/mol | logS: -6.71494 | SlogP: 6.38442 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.103899 | Sterimol/B1: 2.29429 | Sterimol/B2: 4.23036 | Sterimol/B3: 7.60966 |
Sterimol/B4: 8.75975 | Sterimol/L: 21.4994 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 804.918 | Positive charged surface: 511.398 | Negative charged surface: 293.52 | Volume: 498.75 |
Hydrophobic surface: 668.045 | Hydrophilic surface: 136.873 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |