Physical Properties | | | |
Molecular Weight: 374.421 g/mol | logS: -2.76718 | SlogP: 3.1167 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0961223 | Sterimol/B1: 2.10202 | Sterimol/B2: 3.1511 | Sterimol/B3: 4.52238 |
Sterimol/B4: 10.2252 | Sterimol/L: 16.8133 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 631.737 | Positive charged surface: 475.429 | Negative charged surface: 156.308 | Volume: 366.5 |
Hydrophobic surface: 573.771 | Hydrophilic surface: 57.966 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |