Physical Properties | | | |
Molecular Weight: 418.453 g/mol | logS: -5.93748 | SlogP: 3.77522 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0936899 | Sterimol/B1: 2.19027 | Sterimol/B2: 3.06341 | Sterimol/B3: 5.63029 |
Sterimol/B4: 11.9713 | Sterimol/L: 18.1227 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 735.327 | Positive charged surface: 456.727 | Negative charged surface: 278.599 | Volume: 391.375 |
Hydrophobic surface: 569.121 | Hydrophilic surface: 166.206 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |