Physical Properties | | | |
Molecular Weight: 376.867 g/mol | logS: -7.94146 | SlogP: 4.94294 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0587902 | Sterimol/B1: 2.43457 | Sterimol/B2: 3.08291 | Sterimol/B3: 3.74227 |
Sterimol/B4: 11.8205 | Sterimol/L: 15.2858 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 649.289 | Positive charged surface: 352.04 | Negative charged surface: 297.249 | Volume: 362 |
Hydrophobic surface: 569.351 | Hydrophilic surface: 79.938 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 3 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |