Physical Properties | | | |
Molecular Weight: 409.89 g/mol | logS: -3.90168 | SlogP: 1.763 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.328999 | Sterimol/B1: 2.22094 | Sterimol/B2: 5.06767 | Sterimol/B3: 5.20322 |
Sterimol/B4: 9.51664 | Sterimol/L: 13.8039 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 652.75 | Positive charged surface: 469.295 | Negative charged surface: 183.455 | Volume: 386 |
Hydrophobic surface: 538.043 | Hydrophilic surface: 114.707 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |