Physical Properties | | | |
Molecular Weight: 388.895 g/mol | logS: -4.98333 | SlogP: 4.2331 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.11175 | Sterimol/B1: 2.0942 | Sterimol/B2: 3.14261 | Sterimol/B3: 5.7482 |
Sterimol/B4: 11.0475 | Sterimol/L: 16.817 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 648.232 | Positive charged surface: 414.975 | Negative charged surface: 233.257 | Volume: 373.625 |
Hydrophobic surface: 570.955 | Hydrophilic surface: 77.277 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |