Physical Properties | | | |
Molecular Weight: 404.447 g/mol | logS: -4.35178 | SlogP: 2.0973 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.10378 | Sterimol/B1: 2.5654 | Sterimol/B2: 3.77699 | Sterimol/B3: 4.30525 |
Sterimol/B4: 8.35151 | Sterimol/L: 15.9349 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 618.547 | Positive charged surface: 350.27 | Negative charged surface: 268.277 | Volume: 348.125 |
Hydrophobic surface: 360.254 | Hydrophilic surface: 258.293 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |