Physical Properties | | | |
Molecular Weight: 374.465 g/mol | logS: -4.57047 | SlogP: 4.0989 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.10645 | Sterimol/B1: 2.32662 | Sterimol/B2: 3.87896 | Sterimol/B3: 6.14426 |
Sterimol/B4: 7.37303 | Sterimol/L: 16.5177 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 615.768 | Positive charged surface: 343.73 | Negative charged surface: 272.039 | Volume: 345.375 |
Hydrophobic surface: 478.05 | Hydrophilic surface: 137.718 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |