Physical Properties | | | |
Molecular Weight: 411.889 g/mol | logS: -5.54927 | SlogP: 4.27224 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0609218 | Sterimol/B1: 2.18422 | Sterimol/B2: 3.78818 | Sterimol/B3: 5.40639 |
Sterimol/B4: 7.95918 | Sterimol/L: 20.559 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 714.782 | Positive charged surface: 369.048 | Negative charged surface: 345.734 | Volume: 389.375 |
Hydrophobic surface: 607.157 | Hydrophilic surface: 107.625 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |