Physical Properties | | | |
Molecular Weight: 365.385 g/mol | logS: -5.17809 | SlogP: 3.69112 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0525833 | Sterimol/B1: 2.32295 | Sterimol/B2: 3.1218 | Sterimol/B3: 4.82787 |
Sterimol/B4: 7.67495 | Sterimol/L: 20.2344 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 640.753 | Positive charged surface: 377.413 | Negative charged surface: 260.509 | Volume: 346.875 |
Hydrophobic surface: 497.495 | Hydrophilic surface: 143.258 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |