Physical Properties | | | |
Molecular Weight: 487.02 g/mol | logS: -6.43789 | SlogP: 4.68137 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.153079 | Sterimol/B1: 3.79516 | Sterimol/B2: 4.85248 | Sterimol/B3: 4.89132 |
Sterimol/B4: 9.77354 | Sterimol/L: 17.3009 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 733.366 | Positive charged surface: 408.228 | Negative charged surface: 325.137 | Volume: 451.25 |
Hydrophobic surface: 643.818 | Hydrophilic surface: 89.548 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |