Physical Properties | | | |
Molecular Weight: 403.499 g/mol | logS: -4.65931 | SlogP: 3.16038 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0736877 | Sterimol/B1: 2.77231 | Sterimol/B2: 3.87351 | Sterimol/B3: 5.50407 |
Sterimol/B4: 5.67189 | Sterimol/L: 18.3183 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 649.237 | Positive charged surface: 403.06 | Negative charged surface: 246.177 | Volume: 374.875 |
Hydrophobic surface: 563.461 | Hydrophilic surface: 85.776 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |