Physical Properties | | | |
Molecular Weight: 482.963 g/mol | logS: -8.02929 | SlogP: 5.3822 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0424526 | Sterimol/B1: 2.32587 | Sterimol/B2: 2.45335 | Sterimol/B3: 5.16942 |
Sterimol/B4: 9.67281 | Sterimol/L: 18.8246 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 718.995 | Positive charged surface: 372.226 | Negative charged surface: 335.746 | Volume: 420.125 |
Hydrophobic surface: 632.291 | Hydrophilic surface: 86.704 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |