Physical Properties | | | |
Molecular Weight: 398.571 g/mol | logS: -5.49772 | SlogP: 4.06924 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.179535 | Sterimol/B1: 3.1152 | Sterimol/B2: 3.78236 | Sterimol/B3: 7.09705 |
Sterimol/B4: 8.08053 | Sterimol/L: 16.0791 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 691.598 | Positive charged surface: 464.483 | Negative charged surface: 227.115 | Volume: 404 |
Hydrophobic surface: 613.455 | Hydrophilic surface: 78.143 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |