Physical Properties | | | |
Molecular Weight: 420.53 g/mol | logS: -3.29981 | SlogP: 1.8935 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0329587 | Sterimol/B1: 2.38365 | Sterimol/B2: 2.51713 | Sterimol/B3: 5.60184 |
Sterimol/B4: 6.5874 | Sterimol/L: 22.4639 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 723.944 | Positive charged surface: 477.08 | Negative charged surface: 246.864 | Volume: 395.375 |
Hydrophobic surface: 578.725 | Hydrophilic surface: 145.219 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |