Physical Properties | | | |
Molecular Weight: 422.485 g/mol | logS: -4.57762 | SlogP: 3.759 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0226638 | Sterimol/B1: 3.37928 | Sterimol/B2: 3.72639 | Sterimol/B3: 5.35205 |
Sterimol/B4: 8.31348 | Sterimol/L: 18.9251 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 757.102 | Positive charged surface: 495.33 | Negative charged surface: 261.772 | Volume: 408.5 |
Hydrophobic surface: 594.575 | Hydrophilic surface: 162.527 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |