Physical Properties | | | |
Molecular Weight: 416.973 g/mol | logS: -4.70396 | SlogP: 4.9732 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0416427 | Sterimol/B1: 3.22585 | Sterimol/B2: 4.00935 | Sterimol/B3: 4.52183 |
Sterimol/B4: 5.72542 | Sterimol/L: 22.9801 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 723.966 | Positive charged surface: 434.909 | Negative charged surface: 289.058 | Volume: 393.625 |
Hydrophobic surface: 650.456 | Hydrophilic surface: 73.51 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |