Physical Properties | | | |
Molecular Weight: 398.531 g/mol | logS: -5.40317 | SlogP: 3.7124 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0237599 | Sterimol/B1: 2.35484 | Sterimol/B2: 2.47589 | Sterimol/B3: 4.89077 |
Sterimol/B4: 10.3224 | Sterimol/L: 19.6107 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 729.668 | Positive charged surface: 443.611 | Negative charged surface: 281.864 | Volume: 387.875 |
Hydrophobic surface: 557.032 | Hydrophilic surface: 172.636 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |