Physical Properties | | | |
Molecular Weight: 413.521 g/mol | logS: -4.64259 | SlogP: 5.23867 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.154347 | Sterimol/B1: 2.58733 | Sterimol/B2: 2.73418 | Sterimol/B3: 6.22604 |
Sterimol/B4: 12.1486 | Sterimol/L: 17.4312 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 735.824 | Positive charged surface: 510.939 | Negative charged surface: 221.629 | Volume: 419.25 |
Hydrophobic surface: 624.183 | Hydrophilic surface: 111.641 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |