Physical Properties | | | |
Molecular Weight: 402.587 g/mol | logS: -4.83495 | SlogP: 1.53027 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0254588 | Sterimol/B1: 3.56936 | Sterimol/B2: 4.07538 | Sterimol/B3: 4.88942 |
Sterimol/B4: 4.8979 | Sterimol/L: 24.9014 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 762.032 | Positive charged surface: 599.132 | Negative charged surface: 162.9 | Volume: 413.125 |
Hydrophobic surface: 622.19 | Hydrophilic surface: 139.842 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |