Physical Properties | | | |
Molecular Weight: 417.896 g/mol | logS: -7.11947 | SlogP: 4.37179 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0128326 | Sterimol/B1: 2.18347 | Sterimol/B2: 3.42346 | Sterimol/B3: 5.1241 |
Sterimol/B4: 6.31167 | Sterimol/L: 21.8172 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 691.852 | Positive charged surface: 343.222 | Negative charged surface: 348.63 | Volume: 390.5 |
Hydrophobic surface: 591.769 | Hydrophilic surface: 100.083 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |