Physical Properties | | | |
Molecular Weight: 401.466 g/mol | logS: -8.06362 | SlogP: 5.48532 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00787687 | Sterimol/B1: 2.00257 | Sterimol/B2: 2.71772 | Sterimol/B3: 3.26331 |
Sterimol/B4: 8.30898 | Sterimol/L: 23.9427 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 714.416 | Positive charged surface: 449.439 | Negative charged surface: 264.977 | Volume: 390.25 |
Hydrophobic surface: 580.527 | Hydrophilic surface: 133.889 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |