Physical Properties | | | |
Molecular Weight: 431.431 g/mol | logS: -5.18561 | SlogP: 3.86452 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0784877 | Sterimol/B1: 2.66892 | Sterimol/B2: 4.64494 | Sterimol/B3: 4.96972 |
Sterimol/B4: 5.64798 | Sterimol/L: 18.774 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 653.231 | Positive charged surface: 356.369 | Negative charged surface: 296.862 | Volume: 363.75 |
Hydrophobic surface: 443.638 | Hydrophilic surface: 209.593 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |