Physical Properties | | | |
Molecular Weight: 409.465 g/mol | logS: -4.93316 | SlogP: 2.91874 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0386758 | Sterimol/B1: 1.969 | Sterimol/B2: 3.18116 | Sterimol/B3: 4.49139 |
Sterimol/B4: 9.14044 | Sterimol/L: 21.1757 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 704.513 | Positive charged surface: 454.723 | Negative charged surface: 244.137 | Volume: 385.5 |
Hydrophobic surface: 622.392 | Hydrophilic surface: 82.121 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |