Physical Properties | | | |
Molecular Weight: 412.514 g/mol | logS: -3.88717 | SlogP: 3.00926 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.188771 | Sterimol/B1: 2.5128 | Sterimol/B2: 2.77935 | Sterimol/B3: 5.60244 |
Sterimol/B4: 9.23819 | Sterimol/L: 14.2686 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 627.819 | Positive charged surface: 440.169 | Negative charged surface: 184.508 | Volume: 381.75 |
Hydrophobic surface: 501.754 | Hydrophilic surface: 126.065 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |