Physical Properties | | | |
Molecular Weight: 384.432 g/mol | logS: -3.35065 | SlogP: 4.0841 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0803256 | Sterimol/B1: 2.31389 | Sterimol/B2: 3.78308 | Sterimol/B3: 5.22627 |
Sterimol/B4: 8.75042 | Sterimol/L: 16.4632 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 663.101 | Positive charged surface: 519.773 | Negative charged surface: 138.578 | Volume: 367 |
Hydrophobic surface: 545.742 | Hydrophilic surface: 117.359 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |