Physical Properties | | | |
Molecular Weight: 383.495 g/mol | logS: -6.68127 | SlogP: 5.58572 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.190833 | Sterimol/B1: 2.46534 | Sterimol/B2: 3.62217 | Sterimol/B3: 6.48289 |
Sterimol/B4: 6.99713 | Sterimol/L: 16.3961 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 630.181 | Positive charged surface: 400.179 | Negative charged surface: 230.003 | Volume: 382.375 |
Hydrophobic surface: 492.247 | Hydrophilic surface: 137.934 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |