Physical Properties | | | |
Molecular Weight: 376.456 g/mol | logS: -5.75859 | SlogP: 4.18087 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.031479 | Sterimol/B1: 2.44102 | Sterimol/B2: 3.16934 | Sterimol/B3: 4.2299 |
Sterimol/B4: 7.40159 | Sterimol/L: 19.1978 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 633.382 | Positive charged surface: 391.349 | Negative charged surface: 242.033 | Volume: 366 |
Hydrophobic surface: 532.39 | Hydrophilic surface: 100.992 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |