Physical Properties | | | |
Molecular Weight: 420.961 g/mol | logS: -5.4477 | SlogP: 5.41237 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0684302 | Sterimol/B1: 2.57227 | Sterimol/B2: 3.25281 | Sterimol/B3: 7.24417 |
Sterimol/B4: 7.94122 | Sterimol/L: 22.1619 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 751.96 | Positive charged surface: 444.48 | Negative charged surface: 307.479 | Volume: 397.25 |
Hydrophobic surface: 629.59 | Hydrophilic surface: 122.37 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |