Physical Properties | | | |
Molecular Weight: 384.483 g/mol | logS: -5.19612 | SlogP: 4.03744 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0396937 | Sterimol/B1: 3.40594 | Sterimol/B2: 3.7625 | Sterimol/B3: 5.7153 |
Sterimol/B4: 6.29326 | Sterimol/L: 19.8573 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 704.675 | Positive charged surface: 447.795 | Negative charged surface: 256.88 | Volume: 390.5 |
Hydrophobic surface: 622.487 | Hydrophilic surface: 82.188 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |