Physical Properties | | | |
Molecular Weight: 407.643 g/mol | logS: -4.93418 | SlogP: 4.1144 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0613073 | Sterimol/B1: 3.14459 | Sterimol/B2: 3.3089 | Sterimol/B3: 4.3577 |
Sterimol/B4: 10.1253 | Sterimol/L: 19.1629 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 758.673 | Positive charged surface: 586.202 | Negative charged surface: 172.471 | Volume: 445.75 |
Hydrophobic surface: 636.295 | Hydrophilic surface: 122.378 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |