Physical Properties | | | |
Molecular Weight: 462.912 g/mol | logS: -7.67793 | SlogP: 5.8605 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.146446 | Sterimol/B1: 2.52094 | Sterimol/B2: 4.18411 | Sterimol/B3: 5.72574 |
Sterimol/B4: 8.91855 | Sterimol/L: 17.2914 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 675.507 | Positive charged surface: 375.038 | Negative charged surface: 300.469 | Volume: 410.375 |
Hydrophobic surface: 599.442 | Hydrophilic surface: 76.065 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |