Physical Properties | | | |
Molecular Weight: 382.525 g/mol | logS: -4.16292 | SlogP: 2.693 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.168382 | Sterimol/B1: 2.43999 | Sterimol/B2: 2.48471 | Sterimol/B3: 5.41625 |
Sterimol/B4: 11.6728 | Sterimol/L: 13.5403 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 635.15 | Positive charged surface: 434.889 | Negative charged surface: 200.261 | Volume: 369.875 |
Hydrophobic surface: 483.156 | Hydrophilic surface: 151.994 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |