Physical Properties | | | |
Molecular Weight: 397.54 g/mol | logS: -3.30469 | SlogP: 1.13642 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.127251 | Sterimol/B1: 2.00831 | Sterimol/B2: 3.3956 | Sterimol/B3: 5.70745 |
Sterimol/B4: 9.78925 | Sterimol/L: 15.1705 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 671.096 | Positive charged surface: 473.611 | Negative charged surface: 197.485 | Volume: 384.375 |
Hydrophobic surface: 533.79 | Hydrophilic surface: 137.306 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |