Physical Properties | | | |
Molecular Weight: 413.702 g/mol | logS: -6.66749 | SlogP: 5.9691 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.240988 | Sterimol/B1: 3.23656 | Sterimol/B2: 3.2465 | Sterimol/B3: 5.75951 |
Sterimol/B4: 7.48541 | Sterimol/L: 14.1927 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 555.74 | Positive charged surface: 237.761 | Negative charged surface: 317.979 | Volume: 336.125 |
Hydrophobic surface: 517.128 | Hydrophilic surface: 38.612 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |