Physical Properties | | | |
Molecular Weight: 394.289 g/mol | logS: -5.05134 | SlogP: 4.1782 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0860239 | Sterimol/B1: 2.98646 | Sterimol/B2: 3.72661 | Sterimol/B3: 3.93181 |
Sterimol/B4: 9.01152 | Sterimol/L: 16.4648 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 599.435 | Positive charged surface: 294.082 | Negative charged surface: 305.353 | Volume: 322.25 |
Hydrophobic surface: 444.818 | Hydrophilic surface: 154.617 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |